Apolipoproteins: Regulatory Functions, Health Effects and Role in Disease : Regulatory Functions, Health Effects and Role in Disease
Adrik D. Sidorov, Misha Y. Nikitin
Apolipoproteins are proteins that bind lipids (oil-soluble substances such as fat and cholesterol) to form lipoproteins. They transport the lipids through the lymphatic and circulatory systems. Apolipoproteins also serve as enzyme cofactors, receptor ligands, and lipid transfer carriers that regulate the metabolism of lipoproteins and their uptake in tissues. In this book, the authors present current research in the study of the regulatory functions, health effects and role in disease of apolipoproteins. Topics include macrophages, apolipoproteins, steroid hormones and molecular mechanisms of cell proliferation; formation of discoidal apolipoprotein A-1 lipid bound complexes; the role of apolipoprotein E in cardiovascular and renal disease; the functional variants and mutations of the apolipoprotein A5 gene in human pathology; and regulation of FGF-1 of ApoE/HDL generation in astrocytes.
Year:
2012
Edition:
1
Publisher:
Nova Science Publishers, Incorporated
Language:
english
Pages:
166
ISBN 10:
1622574982
ISBN 13:
9781622574988
Series:
Protein Biochemistry, Synthesis, Structure and Cellular Functions
File:
PDF, 8.42 MB
IPFS:
,
english, 2012